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It is a reason to be selective about which peptide and to document the conversation with the patient before the first injection

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The rise in the mitochondrial ROS and increased 8-OHdG expression upon 5-FU administration to the animals in the present study might indicated the similar effect

Additionally, changes in the microenvironment, such as redox state, altered pH, and the presence of reactive oxygen species (ROS) at the pathophysiological sites, can act as sensitive stimuli to trigger drug release in those areas

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PMID: 63 SokolHSeksikP